Hepatitis C virus core antigen testing: Role in diagnosis, disease monitoring and treatment
نویسندگان
چکیده
منابع مشابه
Hepatitis C virus diagnosis and testing.
Development of serological and nucleic acid testing (NAT) has revolutionized hepatitis C virus (HCV) diagnosis. Although third generation anti-HCV enzyme immunoassays (EIAs) are very effective for testing high prevalence populations, confirmatory testing is still necessary when these tests are applied to populations with a low HCV prevalence to exclude false positive results. Limitations of thi...
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DNA coding for the core antigen from hepatitis B Virus (HBcAg) was amplified, cloned and propagated in E. coli. The core protein was expressed in E. coli and the product was readily detected by Western blot. This protein can be used as a diagnostic material in serum screening tests. To increase the level of expression of this antigen in bacteria, two plasmids were constructed in which the gene ...
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Hepatitis C virus infection is a persistent worldwide public health concern. The prevalence of HCV infection is much higher in patients on chronic haemodialysis (HD) than in the general population. HCV infection can detrimentally affect patients throughout the spectrum of chronic kidney disease. Despite the control of blood products, hepatitis C virus transmission is still being observed among ...
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normal. Therefore, the high RI could not be explained by intrarenal abnormalities, pointing to an extrarenal cause. One such cause could be stiffness of the pre-renal arterial vessels. Our patient had suffered from coronary heart disease, insufficiency of the aortic valve and an aneurysm of the ascending aorta. Therefore, 7 years before transplantation, she had undergone to aerotocoronary bypas...
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The correlation and kinetics of hepatitis C virus (HCV) RNA and HCV core antigen levels in chronic hepatitis C patients treated with pegylated interferon + ribavirin were evaluated in order to envision a combined use of the two assays in therapy monitoring. HCV core antigen levels by a chemiluminescent immunoassay (Abbott ARCHITECT) and HCV-RNA levels by branched DNA (bDNA) or real-time PCR hav...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2014
ISSN: 1007-9327
DOI: 10.3748/wjg.v20.i22.6701